Why does your SPE disk need to be dry?

Every step within a solid phase extraction (SPE) procedure is imperative, but one of the most important steps that must be done properly is the air-dry step.  As you may know, the conditioning step prepares the SPE prior to the sample load to ensure that the sample load process will capture the analytes of interest within the media bed.  However, once the sample is done loading, there is a lot of water that is left on the disk.  Depending on the solvents that you are using following sample load and the analytes you are capturing, an improperly dried SPE disk could ruin your day.

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